At this size, two purifiers at opposite ends of the space usually beat one big one: air near a single unit gets cleaned over and over while the far corners wait.
Before you buy for 645 sq ft60 m²
What 645 sq ft60 m² looks like
A large open-plan ground floor: about 23 × 28 ft (7 × 8.5 m)about 7 × 8.5 m (23 × 28 ft). With a 2.5 m ceiling that's 150 m³ of air to pass through a filter 4.8 times an hour.
How the picks differ
Spare air: 40% for the Medify MA-112 and 1% for the Blueair Blue Pure 211i Max. The more air to spare, the slower and quieter it can run here to keep up (more on noise).
Only the Blueair Blue Pure 211i Max has a PM2.5 sensor with auto mode. None has an ionizer.
New filters: every 9 months for the Blueair Blue Pure 211i Max and every 4 months for the Medify MA-112 (filters). The Blueair Blue Pure 211i Max is the most compact at 57.7 cm tall and 7.4 kg; the Medify MA-112 stands 71.9 cm and weighs 14.9 kg.
High ceilings
With a 2.7 m ceiling this room needs 778 m³/h of smoke CADR, with 3 m 864 m³/h. At 3 m only the Medify MA-112 still covers it. For a high ceiling, look at the 861 sq ft80 m² picks. (Why ceilings matter)
Open-plan
If this room opens onto a kitchen or hall with no door between, count it too. Add 216 sq ft and you're at If this room opens onto a kitchen or hall with no door between, count it too. Add 20 m² and you're at 861 sq ft80 m²: of the picks here, only the Medify MA-112 still covers it. (Open-plan spaces)
One purifier or two?
In a long or L-shaped room, two smaller units at opposite ends clean more evenly than one. Two Levoit Core 400S-Ps, each covering 356 sq ft (33 m²), do the job here (In a long or L-shaped room, two smaller units at opposite ends clean more evenly than one. Two Levoit Core 400S-Ps, each covering 33 m² (356 sq ft), do the job here (why two can beat one).
Where to put it
In an open-plan space, put it in the part you use most, or use two, one at each end. (Where to put it)